Navigate to: HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Class\{36fc9e60-c465-11cf-8056-444553540000} (This is the class for USB controllers).
Click and toggle Memory integrity to Off . Restart your computer for changes to take effect. 2. Clean Driver Reinstallation
Download and install the latest HASP drivers from official support sites like Thales Customer Support. 3. Registry Editor Fix (UpperFilters/LowerFilters) mastercam+x72022+virtual+usb+bus+error+39+fixed
In the right pane, look for or LowerFilters and Delete them. Restart your computer. Troubleshooting Additional Causes Mastercam USB HASP issue - eMastercam.com
Fixing the typically requires disabling the Windows Core Isolation (Memory Integrity) security feature, which often blocks the specialized drivers used for HASP keys or virtual USB emulators. Direct Solutions for Error 39 1. Disable Core Isolation (Recommended) mastercam+x72022+virtual+usb+bus+error+39+fixed
If disabling security doesn't work, the driver files may be corrupted. Open (Win + X). Expand Universal Serial Bus controllers .
Check the box for .
: Go to Settings > Update & Security > Windows Security > Device Security .