If you are determined to try it for proof-of-concept reasons, here are the paths currently available: 1. RetroArch (Experimental Cores)
While the Vita has an incredibly active homebrew scene, including the VitaDB repository for community-driven apps, the Sega Saturn's unique hardware presents massive hurdles:
Download the RetroArch VPK from the official site and install it via VitaShell .
Most high-end Saturn emulators like Mednafen (Beetle Saturn) require high single-thread performance that far exceeds the Vita's capabilities. Current Options & Experimental Methods
The Saturn used two CPUs, two GPUs, and multiple dedicated chips for sound and I/O. Replicating this "multi-chip" environment requires more processing power than the Vita's 2011-era CPU can provide.